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| Egypt J Pediatr Allergy Immunol |
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2013 |
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11 |
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63-67 |
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ESP - 2 |
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Original articles |
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| Sesame seed sensitization in a group of atopic Egyptian children |
| Elham Hossny |
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Dalia El-Ghoneimy |
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Dina Soliman |
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Samar Ahmad |
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| Background: There are no published data on the prevalence of sesame
allergy/sensitization in Egypt. Objective: In this pilot study, we thought to
estimate the frequency of sesame seed sensitization in a group of atopic
Egyptian infants and children. Methods: We consecutively enrolled 90
patients with physician diagnosed allergic disease. The study measurements
included clinical evaluation for the site and duration of allergy, history
suggestive of sesame seed allergy, and family history of allergy, as well as
skin prick testing (SPT) using a commercial sesame extract, and serum
sesame specific IgE (SpIgE) estimation. Results: None of the studied
patients reported symptoms suggestive of sesame seed allergy. Nevertheless,
two children (2.2%) showed positive SPT response to sesame (wheal
diameter ? 3 mm above the negative control). Only one of them had a wheal
diameter which exceeded that of the histamine control. The serum sesame
SpIgE exceeded 0.35 IU/ml in all subjects [range = 0.35 - 3.0 IU/ml; median
(IQR) = 0.9 (0.6) IU/ml]. Serum sesame SpIgE was significantly increased
in patients with history of recurrent urticaria (p=0.03). Conclusion: Sesame
seed sensitization is not uncommon in atopic Egyptian children. It can be
associated with any clinical form of allergy and the causal relationship
needs meticulous evaluation. Wider scale population-based studies are
needed to assess the prevalence of sesame allergy and its clinical correlates
in our country. |
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